To reach our aim, a multidisciplinary – interventional, mechanistic, and behavioural – approach will be used in four closely interacting scientific work packages that build on each other’s findings. WP5 deals with implementation and knowledge utilisation, and WP6 with programme management. You can read more about the work packages below.

Work Package 1: FINGER-NL lifestyle intervention

The primary objective of FINGER-NL is to investigate the efficacy of an optimized personalised 2-year multi-domain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.

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Work Package 2: Predictive markers

In WP2 we aim to find easy, cost-effective, non-invasive ways to predict cognitive decline in an early stage and to predict the response to a lifestyle intervention response to prevent cognitive decline.

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Work Package 3: Gut-brain mechanisms

Although beneficial effects of multi-domain lifestyle interventions on cognition in older adults have been shown, the underlying mechanisms still remain to be resolved. However, this understanding is important.

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Work Package 4: Personalised e-Health

WP4 will investigate how to translate the findings of WP1-3 into tangible, meaningful and impactful tools for daily life that support self-management of health in the home environment.

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Work Package 5: Knowledge utilisation

WP5 focuses on optimising knowledge utilisation and implementation by relevant societal and economic partners and ensures proper dissemination of results in science and society.

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Work Package 6: Programme management

The management team is controlled by the Project Council, which consists of a representative of every partner involved in MOCIA and meets every six months.

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